Cassandra Lab

Self-discovering leading-indicator engine — mining cross-vertical event chains for validated "A precedes B" rules.
Tested 9 hypotheses. Treat lift on small n with caution; we report Wilson 95% lower bound + base rate so significance is self-evident.
Trial start precedes trial completion (sanity baseline)
trial_start → trial_complete · window 1095d
validated
n=662hits=448 P=67.7% base=16.1% lift=4.21× conf(95% low)=64.0% median lead=263d
NIH grant precedes clinical trial start
nih_grant → trial_start · window 540d
weak
n=1473hits=471 P=32.0% base=26.2% lift=1.22× conf(95% low)=29.6% median lead=21d
Trial completion precedes SEC 8-K (public sponsor disclosure)
trial_complete → sec_8k · window 120d
weak
n=927hits=0 P=0.0% base=6.1% lift= conf(95% low)=0.0%
Federal award precedes contractor SEC 8-K (material event)
fed_award → sec_8k · window 90d
need more history
n=0hits=0 lift=
n=0 < min sample 8
Federal (research) award precedes trial start
fed_award → trial_start · window 365d
need more history
n=0hits=0 lift=
n=0 < min sample 8
Complaint velocity precedes CPSC recall
complaint → recall · window 120d
need more history
n=0hits=0 lift=
n=0 < min sample 8
FDA recall precedes SEC 8-K
fda_recall → sec_8k · window 90d
weak
n=148hits=0 P=0.0% base=4.6% lift= conf(95% low)=0.0%
CPSC recall precedes SEC 8-K
recall → sec_8k · window 90d
weak
n=226hits=0 P=0.0% base=4.6% lift= conf(95% low)=0.0%
NIH grant precedes sponsor SEC 8-K
nih_grant → sec_8k · window 540d
weak
n=1473hits=0 P=0.0% base=27.4% lift= conf(95% low)=0.0%